Base URL https://api.biopharmawatch.com

BiopharmaWatch API

Programmatic access to biotech catalyst intelligence: FDA & PDUFA calendars with data-driven probability-of-approval scores, clinical pipeline, SEC-derived financial health, hedge-fund & insider signals, options flow, and the full company universe. REST, JSON, one API key.

Plans & access

Two plans. BiopharmaWatch API Basic gives you the full events, reference, and financial-health layer to build on. BiopharmaWatch API Elite Plus adds our proprietary signal layer (Smart Money, machine-learning clinical-trial datasets, options flow) plus 10× throughput.

BiopharmaWatch

API Basic

$99 / mo

Billed annually at $1,190/year

For developers building internal tools, trackers, and their own apps.

Complete FDA calendar with upcoming clinical readouts and PDUFA dates
Probability of Approval (PoA) summary and deep scorecards
5+ years of PDUFA data with decision outcomes and approval status
Historical catalyst data with price movements and key event metadata
Clinical-pipeline database, auto-updated across all monitored companies
SEC financial health: runway, burn, dilution and distress signals
Unusual-volume alerts, company universe, holders, gainers/losers
JSON response format with secure API key authentication
100 requests/min

BiopharmaWatch

API Elite Plus ELITE PLUS

$189 / mo

Billed annually at $2,268/year

For quants, funds, and data-driven investors who want the edge.

Everything in API Basic, plus full access to all platform data in real-time
Company & pipeline scoring: risk-adjusted NPV (rNPV) and valuation signals
M&A target scores, deal tracker, and acquirer leaderboard
Pipeline health grades and competitive landscape intelligence
Hedge-fund positioning and insider-trading activity (Smart Money)
Conviction-weighted hedge-fund sentiment scores
Proprietary machine-learning clinical-trial results and risk signals
FDA designations, approvals and adverse-event safety signals
Options flow, options chain and put-call analytics
Analyst ratings, price targets and firm actions
1,000 requests/min with full historical depth and priority support
Free setup consultation call for custom integration needs

Authentication

Every request takes your API key as the apiKey query parameter. Keys are managed in your account, under API Access (one active key per account; regenerate any time).

curl "https://api.biopharmawatch.com/api/v2/fdacalendar?apiKey=YOUR_API_KEY&ticker=MRNA"

Keep your key secret. It carries your plan's access and rate limit. If a key is exposed, regenerate it from your dashboard and the old key stops working immediately.

Conventions

Topic	Detail
Response envelope	Data is returned under `result` (typically `{ "result": [{ "data": [ … ] }] }`).
Pagination	`page` (50 results/page) on list endpoints.
Dates	`YYYY`, `YYYY-MM` or `YYYY-MM-DD` accepted on date filters.
Rate limits	Per-minute by plan (100 Basic / 1,000 Elite Plus) plus per-endpoint burst caps. `429` when exceeded.
Errors	Non-200 responses carry `{ "error": "…" }`.

FDA Intelligence

The catalyst backbone: upcoming and historical FDA/PDUFA events with probability-of-approval scoring.

GET/api/v2/fdacalendarBASIC

Upcoming FDA catalysts enriched with data-driven PoA scores, regulatory designations, market analysis, and company financials.

Param	Type		Description
`ticker`	string	optional	Filter by ticker (e.g. MRNA)
`drug`	string	optional	Filter by drug name
`phase`	string	optional	Stage (e.g. Phase 3)
`catalyst`	string	optional	PDUFA Date, NDA Filing, and more
`catdateFrom/To`	string	optional	Date range
`page`	integer	optional	Page (50/page)

{
  "result": [{ "data": [{
    "ticker": "MRNA", "drugname": "mRNA-1345",
    "catdate": "2026-06-15", "stage": "Phase 3",
    "catalyst": "PDUFA Date", "treatment": "RSV Vaccine",
    "poa": "72%", "regulatory_designations": ["Fast Track","Priority Review"],
    "therapeuticArea": "Infectious Disease"
  }]}]
}

Full PoA included: both plans return the headline poa %, the poa_summary rationale, and the full score breakdown.

GET/api/v2/fdacalendar/historicalBASIC

Past FDA catalysts with pre and post price-impact analysis (createdDayPrice, catalystDayPrice, percentageChange).

GET/api/v2/pdufa/upcomingBASIC

Upcoming PDUFA dates, NDA & BLA filings with PoA scores and predicted implied volatility.

GET/api/v2/pdufa/historicalBASIC

Historical PDUFA decision records with FDA outcome (Approved, CRL, and more) and company data.

GET/api/v2/fda/designationsELITE PLUS

FDA regulatory designations: Orphan Drug, Fast Track, Breakthrough Therapy, Priority Review, Accelerated Approval.

GET/api/v2/fda/approvalsELITE PLUS

Historical FDA drug-approval records with application type and review designation.

GET/api/v2/fda/adverse-eventsELITE PLUS

FDA adverse-event reports linked to companies and drugs, for safety-signal monitoring.

Clinical Pipeline

Clinical trials mapped to tickers, plus proprietary machine-learning trial outcomes and risk signals.

GET/api/v2/catalystsyncBASIC

Clinical-trial records from ClinicalTrials.gov mapped to tickers: phase, condition, intervention, sponsor, outcomes.

GET/api/v2/clinical-trials/resultsELITE PLUS

Our machine-learning clinical-trial results dataset: primary & secondary endpoints, design-quality and enrollment-velocity risk signals.

Financial Health

SEC-derived survival signals: the "who is about to dilute" layer.

GET/api/v2/sec/company-healthBASIC

Financial-health snapshots with risk class (CRITICAL/DISTRESSED/CAUTIOUS/HEALTHY), cash-runway estimate, burn rate, dilution risk.

{
  "result": [{ "data": [{
    "ticker": "ACAD", "risk_level": "HEALTHY",
    "adjusted_runway": { "adjusted_runway_months": 48.5 },
    "burn_rate": 25000000, "total_liquidity": 1200000000,
    "dilution_risk": "LOW", "market_cap": 4500000000
  }]}]
}

GET/api/v2/sec/company-health/distressedBASIC

The biotech bankruptcy watchlist: CRITICAL/DISTRESSED names sorted by shortest cash runway.

GET/api/v2/sec/financialsBASIC

10-Q quarterly financials from SEC filings: R&D, revenue, assets, debt, cash flow. ticker required.

GET/api/v2/sec/offeringsBASIC

SEC offering filings (S-1, S-3, 424B): shelf offerings that precede capital raises, an early dilution signal.

GET/api/v2/sec/ownershipBASIC

Institutional ownership filings (SC 13D/13G): activist and large institutional moves.

GET/api/v2/sec/proxyBASIC

Proxy-statement data (DEF 14A): executive comp and governance. ticker required.

Smart Money ELITE PLUS

Who is accumulating: 13F holdings for 39 biotech-specialist funds plus insider activity and proprietary sentiment.

GET/api/v2/hedge-fund/holdingsELITE PLUS

Quarterly 13F holdings for biotech specialists (Baker Bros, OrbiMed, RA Capital, Perceptive, RTW, Redmile, EcoR1, and more).

GET/api/v2/hedge-fund/screenerELITE PLUS

Aggregated fund screener: portfolio size, holdings count, top positions.

GET/api/v2/hedge-fund/sentimentELITE PLUS

Proprietary composite sentiment for a ticker (Fund Count 60% / Share Magnitude 25% / Conviction 15%). ticker required.

{
  "result": {
    "ticker": "MRNA", "quarter": "Q4 2025",
    "compositeScore": 0.72, "sentimentLabel": "POSITIVE",
    "activity": { "buyers": 8, "sellers": 2, "newPositions": 3, "exits": 1 }
  }
}

GET/api/v2/insider-tradesELITE PLUS

SEC Form 4 insider buy/sell transactions with trade value and insider position.

GET/api/v2/insider-trades/sentimentELITE PLUS

Monthly insider buy/sell aggregation: buy value, sell value, net, and sentiment for the last 12 months.

Market Signals

Calendar, context, and unusual-volume alerts (Basic), plus options flow (Elite Plus).

GET/api/v2/newsBASIC

Curated biotech news with data-driven summaries and sentiment scores, mapped to tickers.

GET/api/v2/earnings-calendarBASIC

Biotech earnings calendar by month, enriched with company fundamentals.

GET/api/v2/conferencesBASIC

Biotech/pharma conference calendar with dates, locations, details.

GET/api/v2/iposBASIC

Upcoming and pending biotech IPOs: price ranges, deal size, sector.

GET/api/v2/ipos/historicalBASIC

Historical IPOs with computed return (current vs issue price).

GET/api/v2/alerts/unusual-volumeBASIC

Real-time unusual-volume alerts: stocks trading well above average, ranked by unusualness.

GET/api/v2/options/chainELITE PLUS

Options chain grouped by strike: call/put prices, volume, open interest. ticker required.

GET/api/v2/options/summaryELITE PLUS

Aggregate options metrics: total OI, call/put breakdown, put-call ratios. ticker required.

Company Data

The company universe and reference profiles (Basic), plus analyst signals (Elite Plus).

GET/api/v2/companiesBASIC

Biotech company screener enriched with burn rate, cash position, short float, drug types, therapeutic areas, financial stage. Filters: sector, industry, market_cap_min/max.

GET/api/v2/companies/:tickerBASIC

Detailed single-company profile: description, financials, drug types, therapeutic areas. ticker in path.

GET/api/v2/holdersBASIC

Top institutional holders for a stock with share counts and ownership %. ticker required.

GET/api/v2/gainers-losersBASIC

Daily biotech gainers and losers. type = gainers|losers, limit.

GET/api/v2/analyst-ratingsELITE PLUS

Analyst price targets, ratings (Buy/Hold/Sell), and firm actions (Initiated/Upgraded/Downgraded).

Scoring & Valuation ELITE PLUS

Our proprietary scoring cascade: company pipeline scores, risk-adjusted NPV (rNPV), and valuation signals, computed nightly across the full universe. You get the scores, not the rate tables.

GET/api/v2/pipeline/score/:tickerELITE PLUS

Company pipeline score (0 to 100) with grade, valuation signal, total rNPV, percentile rank, and the full 7-factor component breakdown.

{
  "result": {
    "ticker": "BMY", "pipelineScore": 78.4, "pipelineGrade": "A",
    "valuation_signal": "UNDERVALUED", "totalPipelineRNPV_B": 142.6,
    "marketCapB": 98.2, "rNPV_to_mktcap_ratio": 1.45,
    "peerTier": "large_pharma", "percentileRank": 94,
    "components": { "riskAdjustedValue": { "bestAsset": { "drugName": "..." } } }
  }
}

GET/api/v2/pipeline/leaderboardELITE PLUS

Ranked pipeline-score screener across the universe. Filters: grade, valuation, tier, minScore; sort by score, rNPV, or percentile.

GET/api/v2/pipeline/assets/:tickerELITE PLUS

Per-drug risk-adjusted NPV (rNPV) and probability of success (PTRS / LOA) for every scored asset in a company's pipeline, ranked by value.

GET/api/v2/pipeline/intelligence/:tickerELITE PLUS

Unified payload: company score plus scored assets plus trial-level detail plus risk signals plus recent changelog, in one call.

Clinical Intelligence ELITE PLUS

Machine-learning trial risk signals, company pipeline health, the bitemporal change log, and the canonical drug-pipeline reference, all from Clinical Trials 2.0.

GET/api/v2/clinical-trials/risk-signalsELITE PLUS

Trial health scores, enrollment velocity vs benchmark, and design-quality signals. Filter by ticker or nctId.

GET/api/v2/clinical-trials/pipeline-health/:tickerELITE PLUS

Per-company pipeline health grade (A to F) with phase distribution, average enrollment velocity, and critical-risk count.

GET/api/v2/clinical-trials/changelogELITE PLUS

Git-diff for clinical trials: every status, enrollment, and phase change with a severity level (CRITICAL to POSITIVE). Filters: ticker, severity, days.

GET/api/v2/drug-pipeline/:tickerELITE PLUS

Canonical drug-pipeline reference per company: deduplicated assets with modality, indications, best phase, and active trial count.

Competitive Intelligence ELITE PLUS

Who is ahead in every indication: competitive landscapes with phase ranking, enrollment, design quality, and market size.

GET/api/v2/competitive-landscape/company/:tickerELITE PLUS

Every indication where a company competes, with its rank and the top competitors in each.

GET/api/v2/competitive-landscape/indication/:indicationELITE PLUS

Full competitive field for an indication, sorted by competitive strength, with market-size data.

M&A Tracker ELITE PLUS

Acquisition-likelihood scores, curated deal history, and the acquirer leaderboard.

GET/api/v2/ma/target-scoresELITE PLUS

Acquisition-likelihood target scores (10-signal composite) with tier, signal breakdown, and potential acquirers. Filters: ticker, tier, minScore.

GET/api/v2/ma/target-scores/:tickerELITE PLUS

A single target's score, signal breakdown, and any related deals.

GET/api/v2/ma/dealsELITE PLUS

Curated biotech M&A deal history (2019 onward) with value, premium, type, and therapeutic areas. Filters: acquirerTicker, targetTicker, dealType, therapeuticArea.

GET/api/v2/ma/acquirersELITE PLUS

Acquirer leaderboard by deal volume and spend: deal count, total spend, average premium, and deal types.

BiopharmaWatch API v2 · 47 endpoints · Base URL https://api.biopharmawatch.com
Questions or higher volume? support@biopharmawatch.com · Enterprise (bulk, SLA, redistribution) available on request.